Syrian Rue Seeds are perhaps the most concentrated source of Harmala alkaloids which can be found also from many other plants. The seeds are mildly hallucinogenic and have hold a sacred satus in the Middle East and Parts of Asia for hundreds of years.

The seeds of Peganum Harmala contain harmine and harmaline which is why they are generally not sold for human consumption. When they are used to brew Ayahuasca they are usually combined with Mimosa hostilis.

In some countries these substances are classifieds as illegal drugs and possessing or using them may be against the law. Syrian Rue Seeds can be however bought from online stores that are specialized in herbs.